First-Line Approach to GI Disease in Dogs and Cats (Purina Institute Microbiome Forum Round Table 2025)

This quiz is for on-demand attendees of the Purina Institute Microbiome Forum Round Table 2026, “First-Line Approach to GI Disease in Dogs and Cats.” In order to obtain your RACE certificate for 1.5 CE hours, you must get a score of 80% or higher. You can retake the quiz as needed to pass.

This webinar is eligible for RACE credit through 27 January 2027.

1 / 8

Which of the following are important considerations when selecting the most appropriate diet for a dietary trial?

Signalment

Appetite, body weight, and BCS

Presence of GI signs (e.g., vomiting, regurgitation, diarrhea)

Presence of weight loss vs stable weight

All of the above are important considerations when selecting the most appropriate diet.

2 / 8

Why is Peptacetobacter hiranonis (formerly Clostridium hiranonis) a key player in microbiome health and dysbiosis?

P. hiranonis is an opportunistic pathogen that damages the gut barrier.

P. hiranonis is the primary organism responsible for bile acid conversion in dogs and cats.

P. hiranonis is increased in inflammation and is increased in dysbiosis.

P. hiranonis and C. difficile are both increased in dysbiosis and chronic enteropathy.

3 / 8

True or False: low protein digestibility of the diet can induce a dysbiotic-like pattern of the gut microbiome.

True

False

4 / 8

Which of the following therapy sequences presents a microbiome-centric approach to chronic enteropathy in dogs and cats?

Antibiotics; diet change; immunosuppressant

Diet trials (1-3); fecal microbiota transplantation (FMT); immunosuppressant

Diet trial; antibiotic; immunosuppressant

Fecal microbiota transplantation (FMT; diet trial(s); immunosuppressant

5 / 8

True or false: Severe dysbiosis is indicative of more severe ultrastructural and functional changes in chronic enteropathy.

True

False

6 / 8

Regarding the use of dietary trials for diarrhea, which of the following is FALSE?

Dietary management should always be the first approach to diarrhea.

Do not give up after only one food trial: 3-4 trials may be necessary, and at least one of them should be a hydrolyzed food.

The majority of dogs with chronic enteropathy will exhibit clinical remission with diet change.

Diet trials are only indicated when administration of antibiotics or a steroid does not resolve the clinical signs.

7 / 8

Which of the following is FALSE regarding the use of antibiotics for diarrhea?

Antibiotic use results in long-term resolution of clinical signs

The disadvantages of antibiotic use (e.g., dysbiosis, relapse risk, resistance) outweigh the advantages, and antibiotics should only be the last-line approach when other therapies have been exhausted.

Antibiotic-induced dysbiosis can persist for weeks to months after discontinuation of the antibiotic in some animals.

Antibiotics are not recommended for dogs with mild or moderate acute diarrhea, even when blood is observed in the stool, but are potentially indicated for severe disease to treat systemic bacteria.

8 / 8

True or False: Histopathology is reliable for classifying chronic enteropathy and predicting its response to treatment.

True

False

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